Our Science & Pipeline

What are synaptopathies?

The synapses between nerve cells are essential points of communication, transmitting vital information throughout the brain. Synaptic loss and dysfunction drive many brain diseases, collectively known as synaptopathies:

Neurodegenerative
diseases include:

  • Alzheimer’s disease
  • Frontotemporal dementia
  • Huntington’s disease
  • Parkinson’s disease
  • Cochlear and retinal disorders

Neuropsychiatric
diseases include:

  • Schizophrenia
  • Major depressive disorder
  • Bipolar spectrum disorder

Neurodevelopmental
diseases include:

  • Autism spectrum disorder
  • Fragile X syndrome
  • Epilepsy

At Rodin, we’re advancing a unique therapeutic approach to enhance synaptic integrity and improve learning, memory and function in patients living with synaptopathies. Read more about our approach in our publications and supporting literature.